I chose a left-handed keyboard because I'm natively right-handed, but now lefty as a result of repetitive stress injuries to the right side. I chose this particular model because the arrow keys, enter, delete, page up, page down, etc. are all clustered on the left. Most lefty keyboards keep the four arrow keys on the right. But as a computer programmer, I spend much of my time hammering on the arrow keys. Having them on the left is ideal for me. This keyboard did not disappoint.